We’ll talk more about its potential benefits below. It’s also displayed anti-cancer effects in the body. Metabolism of diindolylmethane from cruciferous vegetables ( 20).ĭIM has been shown to support the liver’s detoxification function and control estrogen metabolism to help balance hormones. When digested, I3C then turns into DIM in the human stomach. The compound is derived from glucobrassicin, a natural plant component that becomes broken down into indole-3-carbinol (I3C) when these vegetables are cut or chewed. Here, we take a look at what DIM is, how it may affect your body, and if supplementing with it may be worth looking further into.ĭIM stands for diindolymethane, a natural compound found in cruciferous vegetables, including cabbage, broccoli, cauliflower, kale, Brussels sprouts and more. Men who wish to increase muscle mass with exercise may also want to take DIM.DIM is a particular supplement that has been growing in popularity, especially among women, because it can help correct hormonal imbalances.Īn increasing amount of people are taking DIM supplements to help with issues like acne, premenstrual syndrome (PMS), weight loss and maybe even cancer. Men may benefit from DIM if they have an unhealthy testosterone level, which can cause low moods and a poor libido. The symptoms of premenstrual syndrome (PMS) are some of the most common indications that women may need DIM. The signs that you may need DIM supplements are generally caused by unhealthy levels of testosterone and estrogen. The regimen in this study lasted for 28 days. Prostate health supportĮarly research indicates that DIM may help support prostate health by managing the level of prostate-specific antigen (PSA). Weight managementĭIM may support the management of a healthy weight by reducing the production of estrogen metabolites that are associated with obesity. Menstrual supportĭIM may help to manage menstrual symptoms such as breast discomfort and moodiness. This effect can protect the body from damage by free radicals, especially the brain and heart. These uses include prostate health support, antioxidant support, weight management and the management of menstrual symptoms.ĭIM may help to break estrogen down into metabolites with antioxidant properties. The uses of DIM generally result from its ability to manage hormone levels, especially testosterone and estrogen. The most significant result of this change is a decrease in 16-hydroxyestrone production and an increase in 2-hydroxyestrone production. The primary biochemical role of DIM is to modify the metabolism of estrogen so that it produces more 2-hydroxy estrogen metabolites. Low-temperature steaming is therefore the best method of cooking vegetables while preserving the bioavailability of glucobrassicin. Water also reduces the availability of DIM since glucobrassicin is water soluble. However, some of its bioavailability is still retained since human intestines also contain some myronsinase. Heat breaks down myrosinase, so cooking vegetables reduces the bioavailability of DIM. Indole-3-carbinol quickly breaks down into DIM and other metabolites during the acid-mediated process of digestion. The digestion of glucobrassicin breaks down into indole-3-carbinol and thiocyanate when catalyzed by the enzyme myrosinase, which is also present in cruciferous vegetables. The health benefits of cruciferous vegetables are partially due to the effects of DIM.Ĭruciferous vegetables contain glucobrassicin, which is a type of glucosinolate. These vegetables are members of the cabbage family, which also include broccoli, Brussels sprouts, cauliflower and kale. The primary natural source of DIM is the digestion of cruciferous vegetables. Hormone Balance DIM Background and BenefitsĭIM is an abbreviation for 3,3′-diindolylmethane, which is composed of a methane group with two indole groups attached to it.
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